Lockeridge and its surroundings have provided evidence of Stone and Bronze Age activity in the area. Field enclosures close to the village indicate Roman occupation, whilst the village itself appears in the Domesday Book of 1086.
Lockeridge Dene at the south end of the village is a National Trust site and is a conservation area. Sarsen stones are scattered over the area and this is one of the sites from which the stones at Avebury were mined.